Peer-reviewed papers, conference presentations and application notes — each grounded in a Data4Cure solution and reproducible on the platform.
A domain-adaptation layer aligns pre-clinical and clinical samples in a shared embedding, enabling drug-response prediction across the translational gap.
The CURIE Knowledge Graph is the semantic and contextual layer of the Data4Cure Biomedical Intelligence Cloud — transforming billions of heterogeneous data points into a connected, continuously…
The AI & Insights Layer is the intelligence core of the Data4Cure Biomedical Intelligence® Platform — applying foundation models, knowledge-graph AI, and generative reasoning to turn harmonized data…
The Biomedical App Engine is the computational powerhouse of the Data4Cure Biomedical Intelligence Cloud — a flexible suite of applications, analytics and APIs that move research from exploration to…
The Data Hub is the foundational, semantically-integrated data lakehouse of the Data4Cure Biomedical Intelligence Cloud — ingesting, harmonizing and annotating thousands of public and proprietary…
Data4Cure's CRISPR Cancer Immune Atlas integrates 71 CRISPR screens across 10 datasets — in vitro and in vivo immune challenges and phenotypic screens — into the Biomedical Intelligence Platform to…
A rapidly growing Parkinson's disease resource collection — 66 bulk and 11 single-cell RNA-seq datasets, 3,334 samples and 1,056,893 cells — powers biomarker and target discovery on the Data4Cure…
Two case studies show how the Single-cell RNA-seq Analysis App plugs into the CURIE Knowledge Graph to contextualize immunotherapy response and resistance signatures across independent melanoma datasets.
A worked example of NAFLD and NASH analysis on the Biomedical Intelligence Cloud — semantically-linked datasets, network and pathway integration, and intelligent apps for target, biomarker and…
A worked ulcerative colitis example on the Biomedical Intelligence Cloud — from the HMP2 host transcriptome to FCGR3A, FOXP3, STAT3 and NFKB1 master regulators across 30+ integrated datasets.
Major platform updates: the CURIE Knowledge Graph reaches 1 billion data-driven and literature-mined relations, and a new Data Resources framework brings project-centered curation to the Data Hub.
Data is not knowledge. This perspective argues that context — connecting new results to prior knowledge, other datasets and the literature — is the missing ingredient, and introduces the Biomedical…
Multiscale Maps combine curated pathways with a data-driven ontology (NeXO 2.0) to analyze molecular data at every level of the cellular hierarchy — detecting up to 3× more significant associations…
The Data4Cure Biomedical Intelligence Platform was used to analyze data for the Intensive Trial of OMics in Cancer (ITOMIC) — a distributed-network approach to metastatic triple-negative breast…